Zenakine™ is Croda’s cutting-edge neuroactive ingredient designed to counteract the visible and emotional effects of stress on the skin. Developed in collaboration with SkinBiotherapeutics and based on research from the University of Manchester, Zenakine™ works in sync with the skin’s biological rhythms to restore balance, vitality, and emotional well-being.

Skin & Mind Synergy:

– Boosts melatonin production to support sleep quality and skin regeneration 

– Activates neuroreceptors linked to emotional balance 

– Reduces signs of fatigue and stress-induced aging 

– Enhances skin hydration, smoothness, and radiance 

– Calms redness and improves barrier function 

Clinical Highlights:

– First cosmetic ingredient with instrumental measures on sleep quality and duration 

– Proven efficacy in overnight masks, beauty mists, and face serums 

– Ideal for eye contour care, scalp treatments, and stress-recovery skincare

Sustainability & Compliance

Zenakine™ reflects Croda’s commitment to science-led sustainability:

– Derived from renewable feedstocks 

– Free from parabens, BHT/BHA, EDTA, and synthetic additives 

– RSPO MBAL-certified palm content 

– Fully biodegradable and compliant across Asia, Europe, Latin America, and North America

Zenakine™ is a neurocosmetic active that bridges emotional wellness and visible transformation. Perfect for brands seeking to tap into the growing demand for stress-relief beauty rituals and circadian-aligned skincare.