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The newly patented topical composition by Galderma is designed to address specific skin concerns around the eye area, promoting restoration and brightening. This formulation incorporates various peptides and excipients, meticulously chosen for their synergistic effects in enhancing skin health.

IntrGalderma has recently filed a patent detailing advanced compositions and methods designed to promote skin health, regeneration, repair, and wound healing. The invention focuses on innovative skincare treatments, particularly targeting the delicate skin around the eyes. This article examines

Composition Details:

• Peptides:

The key active ingredients in the composition are specific peptides, including:

Tripeptide-1

Hexapeptide-12

These peptides are included at concentrations ranging from 0.5 to 100 ppm, aimed at stimulating skin regeneration and repair. The formulation also includes:

Palmitoyl Tetrapeptide-7, which is functionalized with palmitoyl or myristoyl groups to enhance its efficacy.

Additionally, the composition can be customized with different amino acid sequences for the tetrapeptide, such as GQPR, KTFK, AQTR, or RSRK, with a preference for GQPR due to its superior performance in promoting skin health.

• Excipients:

To further enhance the formulation’s effectiveness and stability, a range of excipients is incorporated, including:

Caprylic/Capric Triglyceride

Niacinamide

Cyclopentasiloxane

Tocopherol (Vitamin E)

These excipients are selected for their roles in moisturizing, protecting, and nourishing the skin, contributing to the overall benefits of the composition.

•  Formulation:

The topical composition is primarily formulated as a cream, optimized for application around the eye area. The precise combination of peptides and excipients is designed to ensure both efficacy and safety for sensitive skin applications. The cream’s texture and consistency are tailored to facilitate easy absorption and prolonged contact with the skin, maximizing the therapeutic benefits.

Technical Specifications:

The patented composition underscores the importance of precise peptide concentrations and excipient selection:

Peptide Concentrations: 0.5-100 ppm

Preferred Tetrapeptide Sequence: GQPR

Excipients: Caprylic/Capric Triglyceride, Niacinamide, Cyclopentasiloxane, Tocopherol

Applications and Benefits:

The primary focus of this composition is on promoting skin restoration and brightening, particularly around the delicate eye area. The benefits include:

Enhanced Skin Regeneration: Stimulating collagen production and cellular repair.

Skin Brightening: Reducing dark circles and improving skin tone.

Moisturization and Protection: Providing deep hydration and antioxidant protection.

Conclusion:

Galderma’s newly patented skincare composition represents a significant advancement in the field of cosmetic chemistry, offering a targeted solution for eye area skin concerns. The meticulous formulation, featuring specific peptides and carefully chosen excipients, positions this product as a promising innovation in the skincare industry. The patent highlights the potential for customized peptide sequences and excipient combinations to address a wide range of skin health and cosmetic needs, underscoring Galderma’s commitment to pioneering skincare solutions.

Future Directions:

Further research and development could explore additional applications of this peptide-based composition, extending its benefits to other areas of skincare. Continued innovation in peptide technology and formulation techniques will likely yield even more effective and versatile skincare products, reinforcing the importance of patents in protecting and promoting scientific advancements in the cosmetics industry.